Cody Milsom ran for two touchdowns, teammate Asa Adams scored on a 70-yard kickoff return and Knoch opened its Greater Allegheny Conference schedule with a 22-7 upset of visiting Franklin Regional.
Milsom, who rushed for 74 yards on 22 carries, scored on a 1-yard run in the first quarter and a 10-yard run in the. Adams opened the second half with his kickoff return. The Knights also scored on a safety.
Franklin Regional, ranked No. 5 in Class AAA, scored its only points on a 1-yard run by Brett Zanotto in the second quarter.
West Allegheny 55, New Castle 7
Terence Stephens and Whitney White combined to rush for 249 yards and two touchdowns to lead the top-ranked Indians to a Parkway Conference victory at New Castle. Stephens rushed for 143 yards on 10 carries and scored on an 83-yard run. White gained 106 yards on nine carries and scored on a 26-yard run. Chayse Dillon added three touchdowns on runs of 14, 1 and 11 yards.
Central Valley 48, Montour 28
John George ran for two touchdowns and threw for two more as the No. 3 Warriors rolled to an easy victory at Montour. George scored on runs of 39 and 5 yards. He also completed 9 of 12 passes for 189 yards and connected with B.J. Powell on two scoring passes.
Indiana 29, Mars 26
The No. 4 Planets lost tailback Josh Schultheis in the first quarter with a broken tibia, then lost to the Little Indians in this Greater Allegheny Conference opener at Indiana. Schultheis, who entered the season with 3,601 rushing yards, is likely out for the season.
Belle Vernon 44, Trinity 14
The visiting Leopards recorded a Big Nine Conference blowout in coach Matt Humbert's debut against the Hillers.
Laurel Highlands 14, Elizabeth Forward 13
A missed extra point by the Warriors' Tyler Buckley was the difference in this Big Nine Conference opener. Jimmy Pierce scored on runs of 44 and 63 yards for the host Mustangs, while Cameron Lizza connected on both extra points. Jake Meyers scored both Warriors touchdowns on runs of 74 and 17 yards. Meyers rushed for 295 yards.
West Mifflin 38, Uniontown 33
The Titans and Red Raiders combined for 71 points in this Big Nine Conference opener at Uniontown, and West Mifflin came away with the victory.
Greensburg Salem 9, Gateway 6
Coach Tom Nola's debut at Gateway didn't go as expected, as the Gators lost in overtime to the visiting Golden Lions in a Greater Allegheny Conference opener. Ryan Collette's 21-yard field goal in overtime provided the winning points.
Hollidaysburg 31, Yough 6
The Cougars made their debut in the Greater Allegheny Conference with a loss at Hollidaysburg. Zack Weaver scored on runs of 36 and 34 yards to lead the Golden Tigers.
Chartiers Valley 27, Hopewell 21
Dominic Pocci scored on runs of 30 and 28 yards in the fourth quarter to lead the Colts to a Parkway Conference victory against the visiting Vikings. Pocci rushed for 99 yards on five carries. Hopewell was led by Mirko Loncar, who rushed for 203 yards and a touchdown.
Moon 20, Blackhawk 6
Aleksei Yaramus threw for 160 yards and a touchdown and rushed for 99 yards and another score as the Tigers opened their Parkway Conference schedule with a win at Blackhawk. Yaramus scored on a 1-yard sneak and connected with Draper Gilliam on a 17-yard scoring pass.
Hampton 55, Albert Gallatin 0
Nick Grabowski ran for two touchdowns and threw for another as the visiting Talbots beat the Colonials in a non-conference game. Grabowski scored on runs of 40 and 16 yards and connected with Gus Schmitt on a 37-yard scoring pass.