In a game filled with runs, it was Pitt that came up with the hottest streaks at the biggest moments.
The Panthers notched a 17-0 run early in the first half, then outscored Wagner, 17-8, late in the second and ultimately pulled away to win 69-55 Saturday at Spiro Sports Center in Staten Island, N.Y.
Brianna Kiesel posted 19 points to pace the Panthers in scoring for the seventh game, while Bubbles Anderson led a dominating performance in the paint and contributed to a second-half surge.
Anderson made 7 of 9 field goals and scored a career-high 18 points to power Pitt to a 34-18 scoring advantage in the paint. She also recorded six rebounds and four blocks.
"The focus was trying to get the ball inside," Pitt coach Suzie McConnell-Serio said. "When we did, good things happened. We need to continue to have a balanced scoring attack inside and out."
The Panthers' 17-0 run in the first spanned nearly 10 minutes and highlighted Wagner's ice-cold shooting in the first half. Despite the Seahawks going on a 7-0 and 10-2 streak in the first, they connected on just 20 percent of field goals for the half.
Wagner (1-6) opened the second on a 10-2 run and cut the lead to 51-47 with 5:39 to play, but Pitt (5-4) closed the game with help from three key players.
Asia Logan scored all of her eight points in the second half and combined with Anderson and Kiesel to account for 25 of Pitt's final 28 points, securing a victory.
Other district games
■ Niagara 81, Robert Morris 70: With 18 points and 15 rebounds, Artemis Spanou recorded her 31st consecutive double-double in a loss for Robert Morris (3-4) against host Niagara (2-5).
■ West Virginia 94, Fairleigh Dickinson 47: Taylor Palmer scored 25 points, Christal Caldwell had 19 points and five steals, Asya Bussie posted 10 points and 10 rebounds and West Virginia (7-1) cruised at home against Fairleigh Dickinson (1-6).