Washington Redskins (9-7) at New York Giants (10-6), 7 p.m., Thursday
THE SKINNY: The Redskins won their final five games last season to surge to the playoffs. The Giants won their final four games to surge to a Super Bowl victory.
PREDICTION: Giants, 30-13
Houston Texans (8-8) at Steelers (10-6), 1 p.m., Sunday
THE SKINNY: This is the softest part of the Steelers schedule, with the first four games against '07 non-playoff teams. But the Texans aren't soft, they just play in the NFL's toughest division.
PREDICTION: Steelers, 30-14
Cincinnati Bengals (7-9) at Baltimore Ravens (5-11), 1 p.m., Sunday
THE SKINNY: The Bengals have won their past three season openers. After that, it always seems to go downhill. Bad combo for Ravens: Rookie head coach, rookie QB.
PREDICTION: Bengals, 17-13
Detroit Lions (7-9) at Atlanta Falcons (4-12), 1 p.m., Sunday
THE SKINNY: The Falcons are another team with a rookie head coach (Mike Smith) and a rookie QB (Matt Ryan). They also have a new running back, Michael Turner, who finally emerges from LT's shadow.
PREDICTION: Falcons, 24-21
Seattle Seahawks (10-6) at Buffalo Bills (7-9), 1 p.m., Sunday
THE SKINNY: This is supposed to be the final season for Seahawks Coach Mike Holmgren, who has won four division titles in a row. The Bills would settle for one of those division titles.
PREDICTION: Seahawks, 19-13
New York Jets (4-12) at Miami Dolphins (1-15), 1 p.m., Sunday
THE SKINNY: The Jets have won the past four meetings against Miami, and that was before Brett Favre arrived. It was also before they sent Chad Pennington to the Dolphins.
PREDICTION: Jets, 24-17
Kansas City Chiefs (4-12) at New England Patriots (16-0), 1 p.m., Sunday
THE SKINNY: The Patriots are shooting for their 20th regular-season victory in a row, an NFL-record. Even with a rusty Tom Brady, that won't be a problem.
PREDICTION: Patriots, 31-6
Tampa Bay Buccaneers (9-7) at New Orleans Saints (7-9), 1 p.m., Sunday
THE SKINNY: No NFC South team has repeated as division champion, which immediately puts Tampa Bay at a disadvantage. Jeremy Shockey just might be what the Saints need.
PREDICTION: Saints, 23-16
St. Louis Rams (3-13) at Philadelphia Eagles (8-8), 1 p.m., Sunday
THE SKINNY: The Eagles were the only NFC East team to not make the playoffs last season. You know it's bad when Donovan McNabb says he misses Terrell Owens.
PREDICTION: Eagles, 27-14
Jacksonville Jaguars (11-5) at Tennessee Titans (10-6), 1 p.m., Sunday
THE SKINNY: The Titans opened last season with a victory against the Jaguars, who have the league's best winning percentage (.692) on opening weekend. Might they do it again?
PREDICTION: Titans, 23-21
Dallas Cowboys (13-3) at Cleveland Browns (10-6), 4:15 p.m., Sunday
THE SKINNY: Thirteen was the number of victories and players in the Pro Bowl last season for the Cowboys. Seven is the number of consecutive home victories for the Browns.
PREDICTION: Cowboys, 34-20
Carolina Panthers (7-9) at San Diego Chargers (11-5), 4:15 p.m., Sunday
THE SKINNY: The Panthers have their hopes set on a division title after an off-season makeover. The Chargers have their sights set a little higher: Super Bowl.
PREDICTION: Chargers, 31-17
Arizona Cardinals (8-8) at San Francisco 49ers (5-11), 4:15 p.m., Sunday
THE SKINNY: The Cardinals missed the playoffs last season because they lost both meetings with the 49ers. That won't happen again, even with Kurt Warner at quarterback.
PREDICTION: Cardinals, 23-16
Chicago Bears (7-9) at Indianapolis Colts (13-3), 8:15 p.m., Sunday
THE SKINNY: Two debuts for the Colts: Their new stadium and their old quarterback, Peyton Manning, who didn't play in the preseason. Bears can become first NFL team to win 50 season openers.
PREDICTION: Colts, 27-13
Minnesota Vikings (8-8) at Green Bay Packers (13-3), 7 p.m., Monday
THE SKINNY: The Packers won't relinquish their division title without a scrap, even without Brett Favre. They have won the past four meetings against the Vikings.
PREDICTION: Packers, 27-24
Denver Broncos (7-9) at Oakland Raiders (4-12), 10:15 p.m., Monday
THE SKINNY: The Broncos have won four of the past five and eight of 10 against Oakland. But the Raiders won the last meeting in Oakland and just might have the league's best new secondary.
PREDICTION: Raiders, 24-23