CHICAGO -- The Pirates scored the first six runs, but Phil Dumatrait gave them right back and the Chicago White Sox stormed ahead to a 13-8 romp this afternoon at U.S. Cellular Field.

Jermaine Dye homered twice for Chicago and had six RBIs. Orlando Cabrera also homered, giving the White Sox a total of nine in the three-game sweep. The White Sox, who finished with 15 hits today, outscored the Pirates, 37-15.

Dumatrait pitched into the sixth inning and was charged with nine runs on 11 hits to fall to 3-4. He has given up 14 runs in his past two outings, each in an American League park.

"They're a pretty good hitting team, and they showed that," Dumatrait said.

"Things really snowballed," manager John Russell said. "It just seemed like every mistake we made, they hit it hard. I wish you could explain it, but you can't. They have the ability to do that. That's why they're leading the American League in home runs."

The Pirates are 1-5 in interleague play and have fallen five games below .500.

"It's going to get a lot harder when we get home, trust me," first baseman Doug Mientkiewicz said. "Not to take anything away from Chicago, but there are a lot of great lineups in the American League. You fall behind those lineups, you're going to get pounded. The next three series are not any easier."

Those will be against the Toronto Blue Jays, New York Yankees and Tampa Bay Rays.

The Pirates had a 6-0 lead in the second, all on unearned runs: They had bases loaded with two outs for Raul Chavez, who hit a routine bouncer to third. But Pablo Ozuna's throw to second for the forceout was wide, everyone was safe, and a run was across.

Nate McLouth's double into the right-field corner cleared the bases for three more, and Freddy Sanchez lined a home run, his fourth, to left field to make it 6-0.

The three RBIs for McLouth raised his season total to a team-best 51, and Sanchez's home run was his fourth.

"Things looked pretty good for us there," third baseman Jose Bautista said.

But Chicago answered immediately and emphatically.

Jim Thome and Dye opened the bottom half with back-to-back doubles, and seeing-eye singles by Nick Swisher and Alexei Ramirez made it 6-2. Ozuna's one-handed shot into left made it 6-3, and Cabrera's three-run home run -- off a first-pitch fastball by Dumatrait -- tied the score.

Next inning, Dye put the White Sox ahead, 7-6, with a solo home run.

The Pirates answered in the fourth on Sanchez's RBI single for a fresh tie.

Chicago went up again in the fifth, opening with three consecutive singles off Dumatrait, including Thome's RBI liner just past Sanchez's glove.

The White Sox extended that lead to 9-7 in the sixth. Dumatrait gave up Ramirez's single for his final batter. John Grabow relieved and, two batters later, Cabrera's sacrifice fly brought his fourth RBI.

And it was all put to rest in the seventh, when Grabow loaded the bases with no outs and gave up Dye's grand slam.

The Pirates now are 3-12 against Major League Baseball's two Chicago franchises, including 3-9 against the Cubs.

Also today, right fielder Xavier Nady took swings off a tee -- a day earlier than expected -- to test his bruised right shoulder. He will swing again tomorrow. And catcher Ryan Doumit, out two games with a concussion, had a light workout and could be ready tomorrow.

More details in tomorrow's Pittsburgh Post-Gazette.