Outbound lanes of the Parkway East from the Swissvale to Forest Hills exits have reopened.
The highway was closed in that direction earlier tonight while crews removed a vehicle turned on its side.
Pennsylvania State Police in the Pittsburgh barracks said the crash was reported shortly before 8:30 p.m.
An Allegheny County dispatch supervisor said one person has been taken to the hospital. No other vehicles were involved.
No further information was immediately available.