Two children died after a house caught fire in the 900 block of Mirror Street in Greenfield this afternoon.
Their babysitter jumped out the back of the home and was taken to a hospital with head and neck injuries.
Fire Chief Darryl Jones said someone called 911 at 3:21 p.m. to report the fire at 951 Mirror St. Firefighters were dispatched at 3:23 p.m. and arrived three minutes later to find the home nearly engulfed in flames, he said.
Firefighters ran up to the second floor and found one girl in a rear bedroom and a boy in another rear bedroom.
The girl, 3-year-old Irihanna Hayward, died at the scene and the boy, 4-year-old Kamari Thomas, was pronounced dead when he arrived at UPMC Mercy, officials said. Both lived in the house where the fire took place. Officials said they thought the two were related but they were not sure how.
Pittsburgh public safety director Michael Huss said investigators have "absolutely no idea" how the blaze began.
Abbey Brown, 25, who lives in the house next door, said she heard screaming about 3:30 p.m. and saw flames erupting from the building.
Neighbors said a woman outside the home screamed "My babies!" and then, after the first child had been rescued, "One more!"
Neighbors said they saw medics transport a boy and a girl away in ambulances.
Frank Iozzo said he was finishing a maintenance call several houses down the street when he and the customer noticed a commotion.
He ran down the street with a fire extinguisher because he didn't see any smoke.
When he arrived, the fire was raging.
Mr. Iozzo said he couldn't get around the front or side doors so ran to the back of the house, where he saw a woman who was not moving but who was able to talk. He said he called 911.
"It was beyond a fire extinguisher," he said.
Pittsburgh police homicide detectives and Mayor Luke Ravenstahl have arrived at the house.
Liz Navratil: email@example.com, 412-263-1438 and on Twitter @LizNavratil.