Pittsburgh patents

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Patents received Jan. 23, 2007:

Vanderbilt University, for "Methods and systems for facilitating the diagnosis and treatment of schizophrenia, No. 7,166,462." Inventors were Pat Ressler Levitt, Pittsburgh, Venkata Chowdari Kodavali, Vishwajit Laxmikant Nimgaonkar and Karolyn Mirnics, all of Pittsburgh. The present invention relates generally to the field of neurological and physiological dysfunctions associated with schizophrenia. The invention further relates to the identification, isolation and cloning of genes which, when mutated or varied are associated with schizophrenia. The present invention also relates to methods for diagnosing and detecting carriers of the genes and to diagnosis of schizophrenia. The present invention further relates to the construction of animal models of schizophrenia.

PPG Industries Ohio Inc., for "Low gloss powder coating composition, No. 7,166,675." Inventors were Kristin M. Bartlett and Simion Coca, both of Pittsburgh; and Anthony M. Chasser, Allison Park. The present invention relates generally to thermosetting compositions that contain copolymers of vinyl monomers. More specifically, the present invention is directed to a co-reactable solid particulate mixture thermosetting composition that includes functional copolymers containing isobutylene type monomers.

Sepracor Inc., for "Benzo[d]isoxazol-3-ol DAAO inhibitors, No. 7,166,725." Inventors were Q. Kevin Fang, Wellesley, Mass.; Seth Hopkins and Milan Chytil, both of Clinton, Mass.; Michele Heffernan, Worcester, Mass.; and Peter Wipf, Pittsburgh. The enzyme D-amino acid oxidase (DAAO) metabolizes D-amino acids, and in particular, metabolizes D-serine in vitro at physiological pH. DAAO is expressed in the mammalian brain and periphery. D-Serine's role as a neurotransmitter is important in the activation of the N-methyl-D-aspartate (NMDA) selective subtype of the glutamate receptor, an ion channel expressed in neurons, here denoted as NMDA receptor. Small organic molecules, which inhibit the enzymatic cycle of DAAO, may control the levels of D-serine and thus influence the activity of the NMDA receptor in the brain. NMDA receptor activity is important in a variety of disease states, such as schizophrenia, psychosis, ataxias, ischemia, several forms of pain including neuropathic pain, and deficits in memory and cognition.

Seagate Technology LLC, for "Complex transverse AC magneto-optic susceptometer for determination of volume and anisotropy field distribution in recording media, No. 7,166,997." Inventors were Ganping Ju, Wexford; Roy W. Chantrell and Hong Zhou, both of Pittsburgh; and Dieter K. Weller, Gibsonia. The present invention relates generally to methods used to determine magnetic properties of materials. In particular, this invention relates to systems that determine the grain size distribution, .sigma..sub.V, and anisotropy field distribution, .sigma..sub.HK, in thin film granular or nanoparticle material.

NVIDIA Corp., for "Reorganized anisotropic sampling order, No. 7,167,183." Inventors were Walter E. Donovan, Saratoga, Calif.; Anders M. Kugler, Sunnyvale, Calif.; William P. Newhall Jr., San Francisco; and Paul S. Heckbert, Pittsburgh. One or more aspects of the invention generally relate to computer graphics, and more particularly to reading texture map data.


U.S. Patent and Trademark Office, www.uspto.gov


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